Search results for " life span."
showing 3 items of 3 documents
Yeast thioredoxin reductase Trr1p controls TORC1-regulated processes
2018
The thioredoxin system plays a predominant role in the control of cellular redox status. Thioredoxin reductase fuels the system with reducing power in the form of NADPH. The TORC1 complex promotes growth and protein synthesis when nutrients, particularly amino acids, are abundant. It also represses catabolic processes, like autophagy, which are activated during starvation. We analyzed the impact of yeast cytosolic thioredoxin reductase TRR1 deletion under different environmental conditions. It shortens chronological life span and reduces growth in grape juice fermentation. TRR1 deletion has a global impact on metabolism during fermentation. As expected, it reduces oxidative stress tolerance…
Oxidative stress tolerance, adenylate cyclase, and autophagy are key players in the chronological life span of Saccharomyces cerevisiae during winema…
2012
Most grape juice fermentation takes place when yeast cells are in a nondividing state called the stationary phase. Under such circumstances, we aimed to identify the genetic determinants controlling longevity, known as the chronological life span. We identified commercial strains with both short (EC1118) and long (CSM) life spans in laboratory growth medium and compared them under diverse conditions. Strain CSM shows better tolerance to stresses, including oxidative stress, in the stationary phase. This is reflected during winemaking, when this strain has an increased maximum life span. Compared to EC1118, CSM overexpresses a mitochondrial rhodanese gene-like gene, RDL2, whose deletion lead…
INDOVINA CHI VIENE A CENA? QUESTIONI PSICO-SOCIO-GIURIDICHE NEL CICLO DI VITA DELLA COPPIA MISTA
2013
La famiglia, gruppo sociale con storia e che crea storia (Scabini, 1985), è stata negli anni protagonista di numerose trasformazioni nella sua struttura e nelle sue funzioni. Tra le nuove forme familiari oggetto di ricerca in campo psico-sociale vi è le coppia mista determinata anchʾessa da fenomeni demografici ed economici che, a loro volta, hanno richiesto adattamenti sociali e interventi legislativi ad hoc. Lʾanalisi delle caratteristiche della coppia mista consente di esplorare la praticabilità dellʾintegrazione di differenti esperienze culturali a livello di rapporto di coppia, familiare e sociale (Scabini, Regalia e Giuliani, 2007), esprimendo il livello più profondo dʾincontro tra cu…